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國立清華大學化學系 Department of Chemistry
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磯部稔

職    稱：國科會講座教授
學    歷：日本名古屋大學博士(1973)
經    歷：國立清華大學-國科會講座教授 (2008~)
                日本名古屋大學教授 (1991~2008)
                博士後研究：美國哥倫比亞大學 (1973~1975)
辦公室位置：化學館R702
辦公室分機：35608
電子信箱：minoru@mx.nthu.edu.tw

研究專長：

Organic、Natural Product、Bioorganic Chemistry

期刊論文：
  1. Synthetic Study on Sespendole, an Indole Sesquiterpene Alkaloid: Stereocontrolled  Synthesis of the Sesquiterpene Segment Bearing All Requisite Stereogenic Centers. Kumi Sugino, Atsuo Nakazaki, Minoru Isobe, Toshio Nishikawa* Synlett, Published online, DOI: 10.1055/s-0030-1259551.
  2. Suzuki-Miyaura Coupling for General Synthesis of Dehydrocoelenterazine applicable for 6-position Analogs directing toward Bioluminescence Studies. Phakhodee, W.; Toyoda, M.; Jhou J. M.; Khunnawutmanotham, N.; Isobe, M. Tetrahedron, 2011, 67, 1150-1157.
  3. Cyclobutane formation via epoxide opening with sulfone carbanion resulting from heteroconjugate addition. Niyomchon, S.; Cheng, C-Y.; Hasakunpaisarn, A.; Isobe, M. Tetrahedron Lett., published on-line Feb. 19, 2011, DOI 10.1016/ j.tetlet. 2011.01.152.
  4. Chiral Cyclobutane Synthesis by Exploiting a Heteroatom-Directed Conjugate Addition. Tsao K-W.; Isobe, M. Org. Lett., 2010, 12, 5338-5341.
  5. Scalable Synthesis of a New Dihydroxylated Intermediate for Tetrodotoxin and its Analogs, Nishikawa, T.; Hiramatsu, T.; Araki, H.; Isobe, M. Synthesis, 2010, (#12) 1992-1998.
  6. Isobe, M.; Hamajima, A. Total Synthesis of Marine Polyether Toxins, Nat. Prod. Rep., 2010, 27, 1204-1226. DOI: 10.1039/paper no. B919467N.
  7. Tautomycin’s Interactions with Protein Phosphatase 1, Sydnes, M. O.; Isobe, M. Chem. Asian J. 2010, 5, 410-420.
  8. Synthesis of Glycocinnasperimicin D, Taihei Nishiyama,[b] Yoshifumi Kusumoto,[a] Ken Okumura,[a] Kanako Hara,[a], Shohei Kusaba,[a] Keiko Hirata,[b] Yukihiro Kamiya,[b] Minoru Isobe,[b] Keiji Nakano,[a] Hiyoshizo Kotsuki,[a] and Yoshiyasu Ichikawa. Chem. Eur. J. 2010, 16, 600 – 610
  9. Preliminary evaluation and synthesis of tautomycin containing a metal coordinating unit. Sydnes, M. O.; Miyazaki A.; Isobe, M.; Ohinata, H.; Miyazu, M.; Takai, A. Tetrahedron, 2010, 66, 1735-1741.
  10. Synthesis of an Advanced Intermediate Bearing Two Hydroxy Groups for (-)-Tetrodotoxin and Its Analogs. Nishikawa, T.; Koide, Y.; Adachi, M.; Isobe, M.  Bull. Chem. Soc. Jpn, 2010, 83, 66-68.
  11. Differentiation of Coelenteramide Sulfates from Phosphates by means of Hydrogen/Deuterium Exchange with Ion Trap Mass Spectrometry. Doi, I.; Kuse, M.; Nakashima, Y.; Tani, N.; Isobe, M. Journal of the Mass Spectrometry Society of Japan (JMSS), 2009, 57, 89-95.
  12. Prevention of Copper-Induced Calcium Infl ux and Cell Death by Prion-Derived Peptide in Suspension-Cultured Tobacco Cells. Tomoko Kagenishia, Ken Yokawa, Masaki Kuse, Minoru Isobe, François Bouteaua, and Tomonori Kawanoa, Z. Naturforsch. 2009, 64 c, 411 – 417.
  13. A relaxin-like peptide purified from radial nerves induces oocyte maturation and ovulation in starfish,Asterina pectinifera.  Masatoshi Mita*†, Michiyasu Yoshikuni‡¶, Kaoru Ohno‡, Yasushi Shibata‡, Bindhu Paul-Prasanth‡, Suthasinee Pitchayawasin§, Minoru Isobe§, and Yoshitaka Nagahama, Proc. National Academy of Sciences, 2009, 106, 9507-9512.
  14. Oxidatively Induced Cu for Mn Exchange in Protein Phosphatase 1g: A New Method for Active Site Analysis.  Miyazaki, A.; Sydnes, M. O.; Isobe, M.; Ohinata, H.; Miyazu, M.; Takai, A.  Bioorganic Med. Chem., 2009, 17, 7978-7986.
  15. 1H NMR Aided Elucidation of Products Derived from Photodegradation of Ethyl 3-azido-4,6-difluorobenzoate in 2,2,2-Trifluoroethanol. Sydnes, M. O.; Kuse, M.; Doi, I.; Isobe, M. Tetrahedron, 2009,65, 3863-3870.
  16. Selective protein modification by the hydroperoxide intermediate in a photoprotein, aequorin. Issei Doi, Masaki Kuse, Toshio Nishikawa and Minoru Isobe, Bioorg. Med. Chem., 2009, 17, 3399-3404.
  17. Substituent effect of imino-O-arenesulfonates, a coupling partner in Suzuki-Miyaura Reaction for substitution of the Pyrazine Ring: A Study for the Synthesis of Coelenterazine Analogs. Makarasen, A.; Kuse, M.; Nishikwa, T.; Isobe, M. Bull. Chem. Soc. Jpn 2009, 82, 870-878.
  18. Synthesis of four Lysine-linked cereulide analogs showing K+ ionophoric activity as lead compounds for emetic toxin-detection by immunoassays. Makarasen, A.; Nishikawa, T.; Isobe, M. Synthesis, 2009, (#13)2184-2194.
  19. Molecular Heterogeneity of TIME-EA4, a Timer Protein in Silkworm Diapause Eggs. Suthasinee Pitchayawasin-Thapphasaraphong, Naoki Tani, Minoru Isobe, Hidenori Kai, Takuya Kurahashi, Junko Kato, Saikwan Trisunan, Biosci. Biotechnol. Biochem., 2009, 73, 1578-1585.
  20. Elegant Total Synthesis of Natural Product, Chapter 8-Medium size Ether Ring, Isobe, M.; Pattarawarapan, M.; Phakhodee, W.; Charoonniyomporn, S.; Hamajima, A. Submitted on Jan 19, 2009.
  21. Novel Stereocontrolled Synthesis of Highly-functionalized Cyclobutanes by Epoxide Opening through a Carbanion Intermediate in Heteroconjugate Addition. Adachi, M.; Yamauchi, E.; Komada, T.; Isobe, M.Synlett. 2009, 1157-1161.
  22. Total Synthesis of Ciguatoxin. Hamajima, A.; Isobe, M. Angew. Chem. Int. Ed. 2009, 48, 2941-2945.
  23. Higher Structure of Cereulide, an emetic toxin from Bacillus cereus, with special comparison with Valinomycin, an antibiotic from Streptomyces fulvissimus. Makarasen, A.; Yoza, K.; Isobe, M. Chem. Asian J. 2009, 4, 688-698.
  24. Syntheses of N-Acylisoxazolidine Derivatives, related to a partial structure found in Zetekitoxin AB, a golden frog poison. Nishikawa, T.; Urabe, D.; Isobe, M.  Heterocycles, 2009, 79, 379-385.
  25. Regioselectivity of Larock indol synthesis using functionalized alkynes. Sugino, K.; Yoshimura, H.; Nishikawa, T.; Isobe, M. Biosci. Biotech. Biochem. 2008, 72, 2092-2102.
  26. Reductive monoalkylation of nitro aryls in one-pot.  Sydnes, M. O.; Kuse, M.; Isobe, M. Tetrahedron,2008, 64, 6406-6414.
  27. Synthetic Studies and biosynthetic considerations on marine alkaroid chartelline.  Nishikawa, T.; Kajii, Isobe,Chem. Communic. 2008, 3121-3123.
  28. Cysteine 390 is the binding site of luminous substance with symplectin, a photoprotein of Okinawan luminous squid, Symplectoteuthis oualaniensis. Isobe, M.; Kuse, M.; Tani, N.; Fujii, T.; Matsuda, T. Proc. Jpn. Acad., Ser. B. 2008, 84, 386-392.
  29. One-Pot Reductive Monoalkylation of Nitro Aryls with Hydrogen over Pd/C. Sydnes, M.O.; Isobe, M. Tetrahedron Lett., 2008, 49, 1199-1202.
  30. Synthesis of N-Hydroxyenamide, a potential precursor of chartelline.  Kajii, S.; Nishikawa, T.; Isobe, M. Tetrahedron Lett., 2008, 49, 594-597.
  31. C-Glycosylation, Nishikawa, T.; Adachi, M.; Isobe, M. Glycoscience, (Ed. Fraser-Reid, B., Tatsuta, K., Thiem J.)Chapter 3.8, p755-811, Springer-Verlag Berlin Heiderberg, 2008.
  32. Interactions between TIME and PIN could play a role in the system that controls the duration of diapause development and synchronization with seasonal cycles in the silkworm Bombyx mori. Kai, H.; Tani, N.; Isobe, M. Entomol. Res. 2008, 38, 179-187.
  33. Protein Phosphatase Inhibitory Activity of Tautomycin Photoaffinity Probes Evaluated at Femto-molar Level Magne O. Sydnes, Masaki Kuse, Masakuni Kurono, Aya Shimomura, Hiroshi Ohinata, Akira Takai and Minoru Isobe, Bioorg. Med. Chem. 2008, 16, 1747-1755.
  34. Synthesis of N-Hydroxyenamide, a potential precursor of chartelline.  Kajii, S.; Nishikawa, T.; Isobe, M.  Tetrahedron Lett., 2008, 49, 594-597.
  35. One-Pot Reductive Monoalkylation of Nitro Aryls with Hydrogen over Pd/C. Sydnes, M.O.; Isobe, M.,Tetrahedron Lett., 2008, 7, 1199-1202.
  36. Reductive Monoalkylation of Nitro Aryls in One-Pot. Sydnes, M. O.; Kuse, M.; Isobe, M.  Tetrahedron,2008, 64, 6406-6414.
  37. Malyngamide X: The First (7R)-Lyngbic Acid that Connectts to a New Tripeptide Backbone from the Thai Sea Hare Bursatella leachii.   Suntornchashwej, S.; Suwanborirux, K.; Koga, K.; Isobe, M.  Chem. Asian J. 2007, 2, 114-122.
  38. Synthesis of [18,19,21,22-13C4]-Labeled Tautomycin as an NMR probe of protein phosphatase inhibitor. Isobe, M.; Kurono, M.; Tsuboi, K.; Takai, A. Chem. Asia J. 2007, 2, 377-385.
  39. Geldanamycin derivatives and neuroprotective Effect on Cultured P19-derived neurons.  Sarin Tadtong,S.; Meksuriyen, D.; Tanasupawat,S.;  Isobe,M.; Suwanborirux. K.  Bioorg. Med. Chem. Lett. 2007, 17, 2939-2943.
  40. Total synthesis of malyngamide X and its 7’S-epi-Isomer. Suntornchashwej, S.; Suwanborirux, K.; Isobe, M.Tetrahedron 2007, 63, 3217-3226.
  41. Synthesis of the second generation photoaffinity probes of tautomycin. Sydnes, M. O.; Isobe, M.Tetrahedron 2007, 63, 2593-2603.
  42. Synthesis of Symmetric HIJ-ring model of Ciguatoxin.  Nonomiya, A.; Hamajima, A.; Isobe, M.Tetrahedron 2007, 63, 5886-5894.
  43. Determination of Solvent-Trapped Products Obtained by Photolysis of Aryl Azides in 2,2,2-Trifluoroethanol. Sydnes, M. O.; Doi, I.; Ohishi, A.; Kuse, M.; Isobe, M.  Chem. Asian J., 2007, 3, 102-112.
  44. Convergent Synthesis of the Right-Hand Segment of Ciguatoxin.  Hamajima, A.; Isobe, M. Org. Lett. 2006,8(#6), 1205-1208.
  45. Synthesis of b-analogues of C-mannosyltryptophan, a novel C-glycosylamino acid found in proteins. Nishikawa,T.; Koide,Y.; Kanakubo,A.; Yoshimura.H.; Isobe,M. Org. Biol. Chem. 2006, 4, 1268-1277.
  46. Synthesis of Urea-Tethered Neoglycoconjugates and Pseudooligosaccharides in Water.  Ichikawa, Y.; Matsukawa, Y.; Isobe, M.  J. Am. Chem. Soc. 2006, 128(#12), 3934-3938.
  47. Novel Functional Group Transformation from Acetylene Cobalt Complex to Ketone via Ligand Exchange.  Hamajima, A.; Nakata, H.; Goto, M.; Isobe, M.  Chem. Lett. 2006, 35(#4), 464-465.
  48. An Efficient Total Synthesis of Optically Active Tetrodotoxin from Levoglucosenone.  Urabe, D.; Nishikawa, T.; Isobe, M.  Chem. Asian J. 2006, 1-2, 125-135.
  49. The Molecular Mechanism of the Termination of Insect Diapause, Part 1: A Timer Protein, TIME-EA4, in the Diapause Eggs of the Silkworm Bombyx mori is a Metallo-Glycoprotein. Isobe, M.; Kai, H.; Kurahashi, T.; Suwan, S.; Pitchayawasin-T. S.; Franz, T.; Tani, N.; Higashi, K.; Nishida, H.  Chem BioChem. 2006, 7, 1590-1598.
  50. Biological Activity of the Functional Epitope of Ciguatoxin Fragment AB on the Neuroblastoma Sodium Channel in Tissue Culture.  Hokama, Y.; Chun, K. E.; Campora, C. E.; Higa, N.; Suma, C.; Hamajima, A.; Isobe, M.  J. Clinical Laboratory Analysis  2006, 20, 126-132.
  51. One-pot transformation of trichloroacetamide into readily deprotectable carbamates.  Nishikawa, T.; Urabe, D.; Tomita, M.; Tsujimoto, T.; Iwabuchi, T.; Isobe, M.  Org. Lett. 2006, 8, 3263-3265.
  52. Antifungal Azaphilones from the Fungus Chaetomium cupreum CC3003. Kanokmedhakul,S.; Kanokmedhakul,K.; Nasomjai,P.; Louangsysouphanh,S.;  Soytong,K.; Isobe,M.; Kongsaeree, P.; Prabpai, S.; Suksamrarn,A.  J. Nat. Prod. 2006, 69, 891-895.
  53. Time-measurement-regulating peptide PIN may alter a timer conformation of Time Interval Measuring Enzyme (TIME).  Ti, Xiaonan; Tani N.; Isobe, M.; Kai, H.  J. Insect Physiology 2006, 52, 461-467.
  54. Syntheses of Naturally Occurring Terphenyls and Its Related Compounds. Sawayama, Y.; Tsujimoto, T.; Sugino, K.; Nishikawa, T.; Isobe,M.; Kawagishi, H. Biosci. Biotech. Biochem. 2006, 70(#12), 2998-3003.
  55. Molecular Diversity of Valinomycin, a 36-Membered Cyclic Depsipeptide, Which was Detected by Means of HPLC-Q-TOF-MS on Hydrolysate Dipeptides. Pitchayawasin-Thapphasaraphong,S.;  Isobe, M.  ITE Letters on Batteries, New Technologies & Medicine 2006, 7, 465-473.
  56. Synthesis of Urea-Tethered Disaccharides in Water.  Ichikawa, Y.; Matsukawa, Y.; Tamura, M.; Ohara, F.; Isobe, M.; Kotsuki H. Chem. Asian J. 2006, 1, 717-723.
  57. Synthesis of b-analogues of C-mannosyltryptophan, a novel C-glycosylamino acid found in proteins.  Nishikawa, T.; Koide, Y.; Kanakubo, A.; Yoshimura, H.; Isobe, M.  Org. Biomol. Chem. 2006, 4, 1268-1277.
  58. Stereocontrolled Route to Vicinal Diamines by[3.3] Sigmatropic Rearrangement of Allyl Cyanate: Asymmetric Synthesis of anti-(2R,3R)-and syn-(2R,3S)-2,3-Diaminobutanoic Acids.Ichikawa, Y.; Egawa, H.; Ito, T.; Isobe, M.; Nakano, K.; Kotsuki, H. Org. Lett. 2006, 8(#25), 5737-5740.
  59. Tetrabromohydroquinone and riboflavin are possibly responsible for green luminescence in the luminous acorn worm, Ptychodera flava. Kanakubo, A.; Koga, K.; Isobe, M.; Yoza, K.  Luminescence 2005, 20,397-400.
  60.  Regioselective hydrosilylation of terminal acetylenes via asetylene-Co2(CO)4dppm complex;effects of the ligands in acetylenedicobalt complex. Tojo, S.; Isobe, M.  Tetrahedron Lett. 2005, 46, 381-384.
  61. Stereocontrolled Synthesis of the Oxabicyclo[2.2.1]heptane Segment of Solanoeclepin A.  Tojo, S.; Isobe, M.  Synthesis 2005, No.8, 1237-1244.
  62. Stereocontrolled syntheses of a-C-mannosyltryptophan and its analogues.  Nishikwa, T.; Koide, Y.; Kajii, S.; Wada, K.; Ishikawa, M.; Isobe, M.  Org. Biomol. Chem. 2005, 3, 687-700.
  63.  Synthesis of Silylallene Glycosides and Diene Diglycosides by C-Glycosidation of D-Glucal with 1,4-Bis(trimethylsilyl)-2-butyne.  Saeeng, R.; Isobe, M.  Org. Lett. 2005, 7(#8), 1585-1588.
  64. Isolation of brominated quinones showing chemiluminescence activity from luminous acorn worm,Ptychodera flava.  Kanakubo, A.; Isobe, M.  Bioorg. Med. Chem. 2005, 13, 2741-2747.
  65. Novel Synthetic Route of Coelenterazines-2-synthesis of Various Dehydrocoelenterazine Analogs. Kondo. N.; Kuse M.; Mutarapat T,; Thasana, N,; Isobe, M.  J. Heterocyclic Chem. 2005, 65(#4), 843-856.
  66. Synthesis of azide-fluoro-dehydrocoelenterazine analog as a photoaffinity-labeling Probe and Photolysis of azide-fluoro-coelenterazine.  Kuse, M.; Doi, I.; Kondo, N.; Kageyama, Y.; Isobe, M.  Tetrahedron 2005,61, 5754-5762.
  67. Allyl Cyanate-to-isocyanate Rearrangement for the Synthesis of Quaternary Stereocenter with Nitrogen Substituent.  Ichikawa, Y.; Yamauchi, E.; Isobe, M.  Biosci. Biotechnol. Biochem. 2005, 69(#5), 939-943.
  68. Action of aluminum, novel TPC1-type channel inhibitor, against salicylate-induced and cold-shock-induced calcium influx in tobacco BY-2 cells.  Lin, C.; Yu Y.; Kadono, T.; Iwata, M.; Umemura, K.; Furuichi, T.; Kuse, M.; Isobe, M.; Yamamoto, Y.; Matsumoto, H.; Yoshizuka, K.; Kawano, T. Biochem. Biphys. Res. Commun. 2005, 332, 823-830.
  69. Hectochlorin and Morpholine Derivatives from the Thai Sea Hare, Bursatella leachii.  Suntornchashwej, S.; Chaichit, N.; Isobe, M.; Suwanborirux, K. J. Nat. Prod. 2005, 68, 951-955.
  70. Total synthesis of Glycosinnamoylsperimidin D.  Nishiyama, T.; Ichikawa, Y.; Isobe, M.  Angew. Chem. Int. Ed. Engl. 2005, 44, 4372-4375.
  71. Synthesis of (+)-Conagenin.  Matsukawa, Y.; Isobe, M.; Kotsuki, H.; Ichikawa, Y.  J. Org.Chem. 2005,70(#13), 5339-5341.
  72. Stereoselective Allyl Amine Synthesis through Enantioselective Addition of Diethylzinc and [1,3]-Chirality Transfer:  Synthesis of Lentiginosine and Polyoxamic Acid Derivative.  Ichikawa, Y.; Ito, T.; Isobe, M. Eur. J. Chem. 2005,11, 1949-1957.
  73. Stereocontrolled Synthesis of 8,11-Dideoxytetrodotoxin,An Unnaturel Analogue of Puffer Fish Toxin.  Nishikawa, T.; Urabe, D.; Yoshida,K.; Iwabuchi, T.; Asai, M.; Isobe, M. Chem. Euro. J.   2004, 10, 452-462.
  74. Molecular diverrsity of cereulide detected by means of nano-HPLC-ESI-Q-TOF-MS.   Pitchayawasin, S.; Isobe, M.; Kuse, M.; Franz, T.; Agata,N.; Ohta, M.  Int. J. Mass Spectrometry 2004, 235, 123-129.
  75. Novel synthetic route of aryl-aminopyrazine.  Kuse, M.; Kondo, N.; Ohyabu, Y.; Isobe, M.  Tetrahedron2004, 60, 835-840. 
  76. Glycocinnasperimicin D Synthetic Studies:  Synthesis of Cinnamoyl Glycosides via Iodination-Heck Reaction Sequence Starting from Phenyl Glycosides.  Nishiyama, T.; Ichikawa, Y.; Isobe, M.  Synlett 2004, 1,89-92.
  77. A novel stereoselective carbon-chain extension reaction at the C-6 position of 1,6-anhydropyranose.  Nishikawa, t.; Mishima, Y.; Ohyabu, N.; Isobe, M.  Tetrahedron Lett. 2004, 45, 175-178.
  78. Stereoselective Synthesis of the Fully Functionalized HIJ-ring Framework of Ciguatoxin. Baba, T.; Takai, S.; Sawada, N.; Isobe, M.  Synlett  2004, 603-608.
  79. Mass Spectrometric Assignment of Smith Degradation Glycopeptides Derived from Ribonuclease B.   Pitchayawasin, S.; Isobe, M.   Biosci. Biotechnol. Biochem. 2004, 68, 1424-1433.
  80. Synthesis of Model Compound Containing an Indole Spiro-b-lactam Moiety with Vinylchloride in Chartelline.  Nishikawa, T.; Kajii, S.; Isobe, M.  Chem. Lett. 2004, 33,440-441.
  81. Synthesis of photoaffinity probes of tautomycin.  Kurono, M.; Shimomura, A.; Isobe, M.  Tetrahedron2004, 60, 1773-1780.
  82. Differentiation of sulfate and phosphate by H/D exchange mass spectrometry:application to isoflavone.   Kanakubo, A.; Isobe, M.  J. Mass Spectromet. 2004, 39, 1260-1267.
  83. a -C-Mannosyltryptophan is not recognized by conventional mannose-binding lectins.   Nishikawa, T.; Kajii, S.; Sato, C.; Yasukawa, Z.; Kitajima, K.; Isobe, M.   Bioorg. Med. Chem. 2004, 12, 2343-2348.
  84. Structure of pentasaccharide of glycopeptide from TIME-EA4, N-glycoprotein in Silkworm Diapause Eggs.  Pitchayawasin, S.; Isobe, M.; Tani, N.; Kai, H.  Bioorg. Med. Chem. Lett. 2004, 14, 2527-2531.
  85. Synthesis and Physical Nature of Fluorescent Photoaffinity Probe for the Bioorganic Studies on Tautomycin, a Protein Phosphatase Type 1 Selective Inhibitor.  Kurono, M.; Isobe, M. Chem. Lett. 2004,33,452-453.
  86. Stereospecific synthesis of urea-tethered neoglycoconjugates starting from glucopyranosyl carbamates.   Ichikawa, Y.; Nishiyama T.; Isobe, M.  Tetrahedron 2004, 60, 2621-2627.
  87. Aluminum as a specific inhibitor of plant TPC1 Ca2+ channels.   Kawano, T.; Kadono, T.; Fumoto, K.; Lapeyrie, F.; Kuse, M.; Isobe, M.; Furuichi, T.; Muto, S.  Biochem. Biophysic. Res. Communi. 2004, 324,40-45.
  88. Synthesis, Characterization, and Reaction of Crystalline Fisher's Glycopyranosyl Isocyanate.  Ichikawa, Y.; Matsukawa, Y.; Nishiyama, T.; Isobe, M.  Eur. J. Org. Chem. 2004, 586-591.
  89. An Efficient Total Synthesis of Optically Active Tetrodotoxin.  Nishikawa, T.; Urabe, D.; Isobe, M. Angew. Chem. Int. Ed. 2004, 43, 4782-4785.
  90. Urea Glycoside Synthesis in Water.  Ichikawa, Y.; Matsukawa, Y.; Isobe, M.  Synlett 2004, 1019-1022.
  91. Novel Synthesis of Bromoindolenine with Spiro-b-lactam in Chartelline.  Nishikawa, T.; Kajii, S.; Isobe, M. Synlett 2004, 2025-2027.
  92. Demarcation of diapause development by cold and its relation to time-interval activation of TIME-ATPase in eggs of the silkworm, Bombyx mori. Ti, X.; Tuzuki, N.; Tani, N.; Morigami, E.; Isobe, M.; Kai, H.  J. Insect Physiol. 2004, 50, 1053-1064.
  93. Total synthesis of (+)-Blasticidin S.  Ichikawa, Y.; Hirata, K.; Ohbayashi, M.; Isobe, M.  Chem.A Eur. J.2004, 10, 3241-3251. 
  94. A novel deprotection of trichloroacetamide.  Urabe, D.; Sugino, K.; Nishikawa, T.; Isobe, M. Tetrahedron Lett. 2004, 45, 9405-9407.

書藉：
  1. 磯部　稔・西川俊夫、薬学雑誌Review「誌上シンポジウム」 多国間学術拠点形成事業「アジアの最先端有機化学」（斉藤直樹編）YAKUGAKU ZASSHI 2009, 129, 401-406.
  2. 下村脩著（他 共同執筆・磯部　稔・ 村上龍男・長野哲雄・大隅典子・高橋真理子）「クラゲの光に魅せられて」ノーベル化学賞の原点p89-148：朝日新聞社（ノーベル化学賞受賞記念・下村脩講演会−−−パネル討論会「光の魅力、探求する喜び」に加筆修正）2009.6.10.
  3. 磯部　稔・西川俊夫・市川義康「テトロドトキシンの合成 p232-234」「グリコシンアスペリミヂンの合成 p81-82」“天然物の全合成　2000-2008(日本)”分担執筆・有機合成化学協会編・化学同人　2009.6.
  4. 北川　勲・磯部　稔「天然物化学・生物有機化学 I　—天然物化学−」朝倉化学大系13巻369ページ（朝倉書店）2008.5.30
  5. 北川　勲・磯部　稔「天然物化学・生物有機化学 II　—全合成・生物有機化学−」朝倉化学大系14巻278ページ（朝倉書店）2008.6.30
  6. 「天然物の全合成2000-2008日本」有機合成化学協会　submitted June 2008.
  7. 磯部　稔・大藪　紀雄・西川　俊夫：「フグ毒テトロドトキシンの最初の不斉全合成」　有機合成化学協会誌2007 65(#5) pp492-501.

其它：
  1. JSPS Asian Core Program: Cutting-Edge Organic Chemistry in Asia and IUPAC Strategic Planning for a New East and Southeast Asian Network for Organic Chemistry Minoru Isobe,*[a] Toshio Nishikawa,*[b] and Pauline Chiu, Atsushi Nishida (Chiba Univ.), Keisuke Suzuki (Tokyo Institute of Technology), Guo-Qiang Lin (Shanghai Institute of Organic Chemistry), Zhu-Jun Yao (Shanghai Institute of Organic Chemistry), Sunggak Kim (Nanyang Technological Univ., Singapore), Kwan Soo Kim (Yonsei Univ., Seoul), Chulabhorn Mahidol (Chulabhorn Research Institute, Bangkok), Somsak Ruchirawat (Chulabhorn Research Institute, Bangkok), Chun-Chen Liao (National Tsing Hua Univ., Hsinchu), Biing-Jiun Uang (National Tsing Hua Univ., Hsinchu), Henry N. C. Wong (Chinese Univ. of Hong Kong), Teck-Peng Loh (Nanyang Technological Univ., Singapore), Koichi Narasaka (Nanyang Technological Univ., Singapore) Chem/ Asian J. 2010, 5, 660-666.
  2. 磯部　稔・西川俊夫　「多国間学術拠点形成事業・アジアの最先端有機化学」JSPS Asian core Program on Cutting-Edge Organic Chemistry in Asia:  Yakugaku Zasshi 2009, 129(4)401-406.
  3. 下村脩ノーベル賞受賞記念講演会　「パネル討論会」磯部　稔・大隅典子・長野哲雄・村上龍男、朝日新聞全国紙・2009.4.05。
  4. Protocols on safety, efficacy, standardization, and documentation of herbal medicine. Mosihuzzaman, M. et al., Organic and Biomolecular  Chemistry Division,  H. E. J. Research Institute of Chemistry, International Center for Chemical and Biological Pure and Applied Chemistry 2008, 80(10), 2195-2230.

 

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