學歷：

美國明尼蘇達大學博士

期刊論文：(After 2012)

1. The IgE gene in primates exhibits extraordinary evolutionary diversity. Pheidias C. Wu, Jiun-Bo Chen, Shoji Kawamura, Christian Roos, Stefan Merker, Chih-Chin Shih, Ban-Dar Hsu, Carmay Lim, and Tse Wen Chang*. Immunogenetics (2012) 64: 279–287. doi:10.1007/s00251-011-0586-9
    
2. The Effect of Metal Binding on the Characteristic Infrared Band Intensities of Ligands of Biological Interest. Todor Dudev* & Carmay Lim*, J. Mol. Struct. (2012) 1009: 83–88.doi:10.1016/j.molstruc.2011.09.007
    
3. Why voltage-gated Ca2+ and bacterial Na+ channels with the same EEEE motif in their selectivity filters confer opposite metal selectivity.Todor Dudev* & Carmay Lim*, Phys. Chem. Chem. Phys. (2012) 14: 12451–12456. doi:10.1039/C2CP00036A.
    
4. Hidden relationship between conserved residues and locally conserved phosphate-binding structures in NAD(P)-binding Proteins. Chih Yuan Wu, Yun-Hao Hua, Yao Chi Chen & Carmay Lim*, J. Phys. Chem. B(2012) 116: 5644–5652.
    
5. DR.bind: A web server for predicting DNA-binding sites from the protein structure based on electrostatics, evolution and geometry. Yao Chi Chen, Jon Wright and Carmay Lim*,Nucleic Acids Res. (2012) 40: W249–56. doi: 10.1093/nar/gks481.
    
6. Competition among Ca2+, Mg2+, and Na+ for ion channel selectivity filters: Determinants of metal ion selectivity. Todor Dudev* & Carmay Lim*, J. Phys. Chem. B (2012) 116: 10703–10714.DOI:10.1021/jp304925a.
    
7. Calcium Ion Selectivity in Biological Systems.Todor Dudev* & Carmay Lim*, Encyclopedia of Metalloproteins (2013), p. 478–484. Kretsinger, Robert H.; Uversky, Vladimir N.; Permyakov, Eugene A. (Eds.), Springer.
   
    
8. Differential Role of the Protein Matrix on the Binding of a Catalytic Aspartate to Mg2+ vs Ca2+. Application to E. coli Ribonuclease H1.C. Satheesan Babu*, Todor Dudev & Carmay Lim*, J. Am. Chem. Soc. (2013) 135: 6541–6548.
    
9. Protein-protein docking using CHARMM and support vector machine. Application to Ab/Ag Complexes. Jon Wright, Karen Sargsyan, Xiong-wu Wu, Bernie Brooks, and Carmay Lim*,J. Chem. Theory & Comput.(2013) 9: 4186–4194.
    
10. Factors controlling the role of Zn and reactivity of Zn-bound cysteines in proteins: Application to drug target discovery. Yu-Ming Lee, Yeh-fon Lin, and Carmay Lim*, J. Chin. Chem. Soc. (2013) in press. doi: 10.1002/jccs.201300392
     
11. Identification of labile Zn-sites in promising drug-target proteins.Yu-Ming Lee, Yi-Ting Wang, Yulander Duh, Hanna S. Yuan* and Carmay Lim*, J. Am. Chem. Soc. (2013) 135: 14028-14031.
     
12. Competition among metal ions for protein binding sites: Determinants of metal ion selectivity in proteins. Todor Dudev* & Carmay Lim*, Chem. Reviews (2013)
    
     
13. Identifying RNA–Binding Residues based on Evolutionary Conserved Structural and Energetic Features. Yao Chi Chen, Karen Sargsyan, Jon D. Wright, Yi-Shuian Huang* & Carmay Lim*, Nucleic Acids Res.(2014) 42:e15.
     
14. Factors Controlling the Role of Zn and Reactivity of Zn-bound Cysteines in Proteins: Application to Drug Target Discovery. Yu-Ming Lee, Yeh-fon Lin, and Carmay Lim*, J. Chin. Chem. Soc. (2014) 61:142-150.
     
15. Competition among metal ions for protein binding sites: Determinants of metal ion selectivity in proteins. Todor Dudev* & Carmay Lim*, Chem. Rev. (2014) 114:538-556.
     
16. Potential therapeutic antibodies targeting intrinsically disordered regions in membrane-bound IgE in human B lymphocytes. Hsing-Mao Chu, Jon Wright, Yueh-Hsuan Chan, Chien-Jen Lin, Tse Wen Chang* and Carmay Lim*, Nature Communications (2014), doi:10.1038/ncomms4139
     
17. Evolution of Eukaryotic Ion Channels: Principles Underlying the Conversion of Ca²⁺-Selective to Na⁺-Selective Ion Channels. Todor Dudev* & Carmay Lim*, J. Am. Chem. Soc. (2014)136:3553-3559.