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沙晉康

職    稱:榮譽講座教授
最高學歷:美國康乃爾大學博士
辦公室位置:化學館R709
辦公室分機:33349
電子信箱:cksha@mx.nthu.edu.tw

研究專長:

有機合成

期刊論文:

  1. Peng, S.-Z.; Sha, C.-K.Stereoselective Total Syntheses of Guanacastepenes N and OOrg. Lett. 2015, 17, 3486.
     
  2. Chang, T.-Y.; Tu, Y.-P.; Wei, W.-Y.; Chen, H.-Y.; Chen, C.-S.; Lee, Y.-S.; Hunag, J.-J.; Sha, C.-K.Synthesis and Antiproliferative Activities of Ottelione A AnaloguesACS Med. Chem. Lett. 2012, 3, 1075.
     
  3. Lee, H.-Y.; Sha, C.-K. “Stereoselective Total Synthesis of (±)-Peribysin EJ. Org. Chem. 2012, 77, 598
     
  4. Chen, Y.-J.; Hung, H.-C.; Sha, C.-K.; Chung, W.-S.H.” Photochemistry of benzene and quinoxaline fused Δ2-1,2,3-triazolines and their trapping products” Tetrahedron, 201066, 176.
     
  5. Chen, C.-H.; Chen, Y.-K.; Sha, C.-K. “Enantioselective Total Synthesis of Otteliones A and B” Org. Lett. 2010, 12, 1377.
     
  6. Kuo Y.-L.; Dhanasekaran M.; Sha, C.-K. “Total Syntheses of (±)-Axamide-1 and (±)-Axisonitrile-1 via 6-Exo-dig Radical Cyclization J. Org. Chem. 2009, 74, 2033.
     
  7. Liu, K.-M.; Chau, C.-M.; Sha, C.-K. “Intermolecular radical addition reactions of α-iodo cycloalkenones and a synthetic study of the formal synthesis of enantiopure fawcettimineChem. Commun. 2008, 1, 91.
     
  8. Hong A.-W.; Cheng T.-H.; Raghukumar V.; Sha, C.-K.” An Expedient Route to Montanine-Type Amaryllidaceae Alkaloids: Total Syntheses of (−)-Brunsvigine and (−)-Manthine J. Org. Chem., 2008, 73, 7580
     
  9. Jiang, C.-H.; Bhattacharyya, A.; Sha, C.-K. “Enantiospecific Total Synthesis of (−)-Bakkenolide III and Formal Total Synthesis of (−)-Bakkenolides B, C, H, L, V, and XOrg. Lett. 2007, 9, 3241.
     
  10. Sha, C.-K.; Lin, H.-H.; Lin, G.-I.; Lin, Y.-R.; Liang, C.-F.; Chen, C.-H. “Iodocarbocyclization of a-Iodocycloalkanones bearing an Allenyl Side Chain: Synthesis of of Spirocyclic Cycloalkanones” Tetrahedron Lett. 2006, 47, 1167.
     
  11. Sha, C.-K.; Lin, H.-H.; Chang, W.-S.; Luo, S.-Y. “Photoinduced Atom-transfer Cyclization of a-Iodocycloalkanones Bearing an Allenyl Side Chain” Org. Lett. 2004, 6, 3289.
     
  12. Sha, C.-K.; Liao, H.-W.; Cheng, P.-C.; Yen, S.-C. “Synthesis of a Highly Hindered Hydrindanone via alpha-Carbonyl Radical Cyclization: Enantiospecific Formal Syntheses of (-)-Pinguisenol and (-)-alpha-Pinguisene” J. Org. Chem. 2003, 68, 8704.
     
  13. Sha, C.-K.; Hsu H.-Y.; Cheng S.-Y.; Kuo Y.-L. “Synthesis and Diels-Alder reactions of the benzo[4,5]thieno [2,3- c ]pyrrole ring system ” Tetrahedron 2003, 59, 1477.
     
  14. Sha, C.-K.; Chau, C.-M. “ Total Synthesis of (±)-lentiginosine and (±)-1-epi- lentiginosine from hexahydro-1H-indol-3-one ” Tetrahedron Lett. 2003, 44, 499.
     
  15. Sha, C.-K.; Mohanakrishnan, A. K. “1,3-Dipolar Cycloaddition of Azides,” In “1,3-Dipolar Cycloaddition” A. Padwa and W. Pearson ed., Wiley-Interscience, New York, 2002, Chapter 9, 623.
     
  16. Sha, C.-K.; Huang, S.-J.; Zhan, Z.-P. “Anionic Cyclization Approach Toward      Perhydrobenzofuranone : Stereocontrolled Synthesis of Hexahydrobenzofuran Subunit of Avermectin” J. Org. Chem. 2002, 67, 831.
     
  17. Sha, C.-K.; Ho, W.-Y.; Mohanakrishnan, A. K.; Lin, C.-L.; Chu, SS.-Y. “1,5-Hydrogen atom transfer from α, β and γ carbons to an alkenyl or aryl radical in cycloalkanones” C.R. Acad. Sci. Paris, Chimie / Chemistry 2001, 4, 439.
     
  18. Sha, C.-K.; Hong, A.-W.; Huang, C.-M. “Synthesis of Aza Bicyclic Enones via Anionic cyclization: Application to the Total Synthesis of (-)-Brunsvigine” Organic Lett. 2001, 3, 2177.
     
  19. Sha, C.-K.; Lee, F.-C; Lin, H.-H. "AlCl3/ICl-Mediated iodo-carbocyclization of α–iodo cycloalkanones: a new entry to spirocyclic ketones" J. Chem. Soc., Chem. Commun. 2001, 39.
     
  20. Sha, C.-K.; Tseng, C.-T; Chang, W.-S. "Synthesis of β-substituted α-iodo cycloalkanones by the CuI-mediated conjugate addition of Grignard reagents to α-iodo cycloalkenones" Tetrahedron Lett. 2001, 42, 683.
     
  21. Sha, C.-K.; Huang, S.-J.; Huang, C.-M.; Hong, A.-W.; Jeng, T.-H. "Anionic cyclization approach toward perhydroindoles. Total synthesis of montanine-type Amaryllidaceae alkaloids " Pure and Applied Chem. 2000, 72, 1773.
     
  22. Sha, C.-K.; Zhan, Z.-P; Wang, F.-S. "Cyclization of Alkenyl Radicals in 5- and 6-         (π-Exo)-exo-dig Modes : New Entry to Exo-cyclic Dienes" Organic Lett. 2000, 2, 2011.
     
  23. Sha, C.-K.; Hsu, C.-W.; Chen, Y.-T.; Cheng, S.-Y. "1,5-Hydrogen atom transfer/radical cyclization of cycloalkanones bearing a β-iodo α,β-unsaturated ester or nitrile side chain" Tetrahedron Lett. 2000, 41, 9865.
     
  24. Sha, C.-K.; Lee, F.-K.; Chang, C.-J. "First Total Synthesis of (+)-Paniculatine via Tandom Radical Cyclization Initiate by an α-Carbonyl Radical " J. Am. Chem. Soc. 1999, 42, 9875.
     
  25. Sha, C,-K; Ho, W,-Y. " Total Synthesis of Dimethyl Gloiosiphone A via α-Carbonyl Radical Spiro-cyclization, " J. Chin. Chem. Soc., 1999, 46, 469.
     
  26. Sha, C,-K; Ho, W,-Y. "α-Carbonyl Radical Cyclization Approach Toward Spiro[4,4]nonene: Total Synthesis of Dimethyl Gloiosiphone A" Chem. Commun. 1998, 2709.
     
  27. Sha, C.-K.; K. C. Santhosh; Lih, S.-H. "α-Carbonyl Radical Cyclization Approach Toward Angular Triquinanes: Total Synthesis of Enantiomerically Pure (-)-5-Oxosilphiperfol-6-ene" J. Org. Chem. 1998, 63, 2699.
     
  28. Sha, C.-K.; K. C. Santhosh; Tseng. C.-T.; Lin, C.-T. "Radical Cyclization ofα-iodo enones by photoinduced electron transfer reaction " J. Chem. Soc., Chem. Commun. 1998, 397.
     
  29. Sha, C.-K.; Lee, S.-J.; Tseng, W.-H. "Synthesis of Enantiomerically Pure Desmethyl C,D-Ring Derivative of Paclitaxel (TaxolTM) via Asymmetric Diels-Alder Reaction of 2-Siloxyfuran" Tetrahedron Lett. 1997, 38, 2725.
     
  30. Sha, C.-K.; Chiu, R.-T.; Yang, C.-F.; Yao, N.-T. and Tseng, W.-H.  "Total Synthesis of (-)-Dendrobine viaα-Carbonyl Radical Cyclization" J. Am. Chem. Soc. 1997, 119, 4130.
     
  31. Sha, C.-K.; Tseng, W.-H.; Huang,K.-T.; Liu, K.-M.; Lin, H.-Y.; Chu, S.-Y. "Radical Cyclization Reactions of 4-Bromo Vinylogous-Esters, Vinylogous-Amides, and Enones" J. Chem. Soc., Chem. Commun. 1997, 239.

專利:

  1. Sha, C.-K.; Yang, C.- F.; Chang, C.- J.; Lee, H.- J. “Trimethine cyanine and its use”, US 20130060046 A1 (2013).
     
  2. 楊政奮蕭水生張慶榮李新壬沙晉康螺二氫茚花菁染料及其用途” 中華民國專利發明第一三九九四一一號,中華民國一0二年六月二十一日。
     
  3. 楊政奮李新壬沙晉康“三次甲基花青化合物及其應用”中華民國專利發明第一三七四一六五號,中華民國一0一年十月十一日。
     
  4. Sha, C.-K.; Yang, C.- F.; Lee, H.- J. “Trimethine cyanine compounds and preparation for optical recording disk US 20100068442 A1 (2010).
     
  5. 楊政奮張慶榮程平昌顏光甫洪安威沙晉康含有機金屬錯合物之酞菁化合物及其用途” 中華民國專利發明第一三四二三二四號,中華民國一00年五月二十一日。
     
  6. Sha, C.-K.; Yang, C.- F.; Cheng, P.-C.; Chang, C.-J.; Yen, K.-F.; Hong, A.-W.Metallocenyl phthalocyanine compounds and use thereof in recording layer of writable optical disk US 20080220367 A1(2008).
     
  7. 邱永城陳華夫沙晉康由雜多環單體聚合衍生的電彩材料” 中華民國專利發明第一五三六六0號,中華民國八十年三月十一日。

 

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